Ana Maria Baptista Menezes, Pedro Curi Hallal, Fernando Silva, Marcos Souza, Luciene Paiva, Aline D'Ávila, Bianca Weber, Viviane Vaz, Fernando Marques, Bernardo L. Horta

J Bras Pneumol.2004;30(3):223-228

Letters to the Editor

Trends in tuberculosis mortality among children and adolescents in Brazil, 1996-2020: a joinpoint analysis

Tendências da mortalidade por tuberculose em crianças e adolescentes no Brasil, 1996-2020: análise de pontos de inflexão

Tyele Goulart Peres1, Yasmin Marques Castro2, Mariana Lima Corrêa3, Leonardo Ramos Emmendorfer4, Linjie Zhang5

J Bras Pneumol.2023;49(3):e20230019

Original Article

Prevalences of asthma and rhinitis among adolescents in the city of Fortaleza, Brazil: temporal changes

Comparação temporal das prevalências de asma e rinite em adolescentes em Fortaleza, Brasil

Maria de Fátima Gomes de Luna, Gilberto Bueno Fischer, João Rafael Gomes de Luna, Marcelo Gurgel Carlos da Silva, Paulo César de Almeida, Daniela Chiesa

J Bras Pneumol.2013;39(2):128-137

Evaluation of the impact that the changes in tuberculosis treatment implemented in Brazil in 2009 have had on disease control in the country

Avaliação do impacto das mudanças do tratamento da tuberculose implantadas em 2009 no controle da tuberculose pulmonar no Brasil

Marcelo Fouad Rabahi, José Laerte Rodrigues da Silva Júnior, Marcus Barreto Conde

J Bras Pneumol.2017;43(6):437-444

Letters to the Editor

Prescribing trends in and perceptions of the treatment of asthma: a survey among pulmonologists in Brazil

Tendências prescritivas e percepções no tratamento da asma: um inquérito entre pneumologistas brasileiros

José Eduardo Delfini Cançado1,a, Rodrigo Abensur Athanazio2,b, Luis Fernando Rensi Cunha3,c, Marcia Margaret Menezes Pizzichini4,d

J Bras Pneumol.2019;45(5):e20190083

Original Article

Lung cancer, cancer of the trachea, and bronchial cancer: mortality trends in Brazil, 1980-2003

Tendência de mortalidade do câncer de pulmão, traquéia e brônquios no Brasil, 1980-2003

Deborah Carvalho Malta, Lenildo de Moura, Maria de Fátima Marinho de Souza, Maria Paula Curado, Airlane Pereira Alencar, Gizelton Pereira Alencar

J Bras Pneumol.2007;33(5):536-543

Differences in the clinical and radiological presentation of intrathoracic tuberculosis in the presence or absence of HIV infection

Diferenças na apresentação clínico-radiológica da tuberculose intratorácica segundo a presença ou não de infecção por HIV

Pedro Dornelles Picon, Maria Luiza Avancini Caramori, Sérgio Luiz Bassanesi, Sandra Jungblut, Marcelo Folgierini, Nelson da Silva Porto, Carlos Fernando Carvalho Rizzon, Roberto Luiz Targa Ferreira, Tânia Mariza de Freitas, Carla Adriane Jarczewski

J Bras Pneumol.2007;33(4):429-436

Treatment completion and challenges in rolling out 12-dose weekly rifapentine plus isoniazid to prevent tuberculosis among people living with HIV and pediatric household contacts in Brazil

Isadora Salles1, Jamile Garcia de Oliveira2, Alexandra Brito de Souza3, Silvia Cohn1, Renata Spener-Gomes4,5, Solange Dourado de Andrade3, Valeria Saraceni2, Solange Cesar Cavalcante2,6, Jeff Weiser7, Makaita Gombe7, Violet Chihota7,8,9, Gavin Churchyard7,8,9, Richard E Chaisson1, Marcelo Cordeiro-Santos3,4,10, Betina Durovni2,11

J Bras Pneumol.2025;51(4):e20250125

Objective: In July of 2021, the Brazilian National Ministry of Health integrated three months of once-weekly isoniazid plus rifapentine (3HP) into the National Guidelines for Tuberculosis Control as a first-line tuberculosis preventive therapy (TPT) option for people living with HIV (PLHIV) and tuberculosis household contacts (HHCs). As part of the Unitaid-sponsored Increasing Market and Public Health Outcomes through Scaling up Affordable Access Models of Short Course Preventive Therapy for TB project to implement short-course TPT, we evaluated 3HP uptake, completion, and tolerability among PLHIV and pediatric HHCs in Brazil. Methods: We conducted a multicenter single-arm pragmatic project to roll out 3HP for PLHIV and HHCs in the 2- to 14-year age bracket in the cities of Rio de Janeiro and Manaus, Brazil. Participants were identified, treated, and monitored in accordance with Brazilian national tuberculosis guidelines. De-identified patient-level data on treatment initiation, adverse events, and completion were collected and analyzed. Results: From October of 2021 to March of 2023, 380 PLHIV (77.6% of whom were male; median age, 40 years [IQR, 31-51]) and 74 HHCs (54.1% of whom were male; median age, 8.6 years [IQR, 5.1-11.8]) were enrolled in the study. Treatment completion rates were 83.7% among PLHIV and 82.4% among HHCs. Completion rates were higher in Rio de Janeiro than in Manaus (PLHIV: 86.0% vs. 79.6%; HHCs: 85.2% vs. 80.9%), although completion of 10 doses was similar (PLHIV: 86.4% vs. 86.1%). Adverse event-related discontinuation was low (PLHIV: 2.4%; HHCs: 2.7%). One person living with HIV developed active tuberculosis during treatment. At six months of follow-up, 99.6% of the PLHIV remained free of tuberculosis. Conclusions: The 3HP regimen was successfully introduced, had high treatment completion rates, and was well tolerated. Widespread use of 3HP for TPT may accelerate tuberculosis elimination in Brazil.

Keywords: Tuberculosis; Latent tuberculosis; HIV infections; Isoniazid; Rifapentine; Treatment adherence and compliance.

Temporal evolution of and factors associated with asthma and wheezing in schoolchildren in Brazil

Evolução temporal e fatores associados a asma e sibilância em escolares no Brasil

Gabriela Ávila Marques1,2,a, Andrea Wendt2,b, Fernando César Wehrmeister2,c

J Bras Pneumol.2019;45(3):e20180138

Trends in asthma mortality in the 0- to 4-year and 5- to 34-year age groups in Brazil

Tendências da mortalidade da asma nas faixas etárias de 0 a 4 anos e 5 a 34 anos no Brasil

Gustavo Silveira Graudenz1,2, Dominique Piacenti Carneiro1, Rodolfo de Paula Vieira1

J Bras Pneumol.2017;43(1):24-31

Special Article

Current use and acceptability of novel diagnostic tests for active tuberculosis: a worldwide survey

Uso atual e aceitabilidade de novos testes diagnósticos para tuberculose ativa: um inquérito mundial

Massimo Amicosante1,2A, Lia D'Ambrosio3,4, Marcela Munoz5, Fernanda Carvalho de Queiroz Mello6, Marc Tebruegge7,8,9, Novel Njweipi Chegou10, Fouad Seghrouchni11, Rosella Centis3, Delia Goletti12, Graham Bothamley13, Giovanni Battista Migliori3, TB Diagnostic Survey Working Group

J Bras Pneumol.2017;43(5):380-392

Original Article

A critical analysis of the decreasing trends in tuberculosis cure indicators in Brazil, 2001–2022

Gabriel Pavinati1, Lucas Vinícius de Lima1, Pedro Henrique Paiva Bernardo1, Jhenicy Rubira Dias2, Bárbara Reis-Santos3, Gabriela Tavares Magnabosco1

J Bras Pneumol.2024;50(2):e20240018

Correspondence

A critical analysis of the decreasing trends in tuberculosis cure indicators in Brazil

Hinpetch Daungsupawong1, Viroj Wiwanitki2

J Bras Pneumol.2024;50(4):e20240186

Original Article

Efficacy of the scoring system, recommended by the Brazilian National Ministry of Health, for the diagnosis of pulmonary tuberculosis in children and adolescents, regardless of their HIV status

Eficácia do sistema de pontuação, preconizado pelo Ministério da Saúde, para o diagnóstico de tuberculose pulmonar em crianças e adolescentes infectados ou não pelo HIV

Cinthia Pedrozo, Clemax Couto Sant'Anna, Maria de Fátima B. Pombo March, Sheila Cunha Lucena

J Bras Pneumol.2010;36(1):92-98

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