Original Article

PLATINO, a nine-year follow-up study of COPD in the city of São Paulo, Brazil: the problem of underdiagnosis

PLATINO, estudo de seguimento de nove anos sobre DPOC na cidade de São Paulo: o problema do subdiagnóstico

J Bras Pneumol.2014;40(1):30-37

Objective: To determine the underdiagnosis rate in new COPD cases at the end of a nine-year follow-up period-in the study designated "Projeto Latino-Americano de Investigação em Obstrução Pulmonar" (PLATINO, Latin-American Pulmonary Obstruction Investigation Project)-and compare that with the underdiagnosis rate during the initial phase of the study, as well as to identify the clinical features exhibited by the subjects who were not diagnosed until the end of the follow-up phase. Methods: The study population comprised the 1,000 residents of the city of São Paulo, Brazil, who took part in the PLATINO study. Of those, 613 participated in the follow-up phase, during which the subjects were assessed with the same instruments and equipment employed in the initial phase of the study. We used the chi-square test or the independent sample t-test to analyze the underdiagnosis rate and to identify the characteristics of the subjects who were not diagnosed until the end of the follow-up phase. Results: The underdiagnosis rate for new COPD cases at the end of the nine-year follow-up period was 70.0%. The underdiagnosis rate during the follow-up phase was 17.5% lower than that reported for the initial phase of the study. The subjects who were not diagnosed until the end of the follow-up phase presented with fewer respiratory symptoms, better pulmonary function, and less severe disease than did those previously diagnosed with COPD. Conclusions: The underdiagnosis rate for new COPD cases was lower in the follow-up phase of the study than in the initial phase. The subjects who were not diagnosed until the end of the follow-up phase of the PLATINO study presented with the same clinical profile as did those who were not diagnosed in the initial phase. These findings underscore the need for spirometry in order to confirm the diagnosis of COPD and provide early intervention.

Keywords: Pulmonary disease, chronic obstructive/diagnosis; Pulmonary disease, chronic obstructive/epidemiology; Spirometry.

Underdiagnosis of COPD at primary health care clinics in the city of Aparecida de Goiânia, Brazil

Subdiagnóstico de DPOC na atenção primária em Aparecida de Goiânia, Goiás

Maria Conceição de Castro Antonelli Monteiro de Queiroz, Maria Auxiliadora Carmo Moreira, Marcelo Fouad Rabahi

J Bras Pneumol.2012;38(6):692-699

Anthropometric status of individuals with COPD in the city of São Paulo, Brazil, over time - analysis of a population-based study

Análise evolutiva antropométrica em indivíduos com DPOC na cidade de São Paulo - estudo de base populacional

Josiane Marchioro1,a, Mariana Rodrigues Gazzotti1,b, Graciane Laender Moreira1,c, Beatriz Martins Manzano1,d, Ana Maria Baptista Menezes2,e, Rogélio Perez-Padilla3,f, José Roberto Jardim1,g, Oliver Augusto Nascimento1,4,h, PLATINO Team

J Bras Pneumol.2019;45(6):e20170157

Evaluation of von Willebrand factor in COPD patients

Avaliação do fator de von Willebrand em pacientes com DPOC

Thiago Prudente Bártholo, Cláudia Henrique da Costa, Rogério Rufino

J Bras Pneumol.2014;40(4):373-379

Outcomes of tuberculosis treatment among inpatients and outpatients in the city of São Paulo, Brazil

Desfechos de tratamento de tuberculose em pacientes hospitalizados e não hospitalizados no município de São Paulo

Mirtes Cristina Telles Perrechi, Sandra Aparecida Ribeiro

J Bras Pneumol.2011;37(6):783-790

Tuberculosis recurrence in a priority city in the state of São Paulo, Brazil

Recorrência de tuberculose em município prioritário do estado de São Paulo

Amadeu Antonio Vieira1,2, Danila Torres Leite3, Solange Adreoni2

J Bras Pneumol.2017;43(2):106-112

Lung function of patients hospitalized with COVID-19 at 45 days after hospital discharge: first report of a prospective multicenter study in Brazil

Função pulmonar de pacientes hospitalizados com COVID-19, 45 dias após a alta hospitalar: primeiro relato de um estudo multicêntrico prospectivo no Brasil

Eliane Viana Mancuzo1, Carolina Coimbra Marinho1, George Luiz Lins Machado-Coelho2, Aline Priscila Batista2, Jacqueline Ferreira Oliveira3, Bruno Horta Andrade1, Álvaro Lucca Torres Brandão1, Ana Sophia Mitre Leite4, Pedro Chaves Ferreira1, José Reinaldo Corrêa Roveda1, Arnaldo Santos Leite1, Valéria Maria Augusto1

J Bras Pneumol.2021;47(6):e20210162

Descriptive study of the frequency of nontuberculous mycobacteria in the Baixada Santista region of the state of São Paulo, Brazil

Estudo descritivo da freqüência de micobactérias não tuberculosas na Baixada Santista

Liliana Aparecida Zamarioli, Andréa Gobetti Vieira Coelho, Clemira Martins Pereira, Ana Carolina Chiou Nascimento, Suely Yoko Mizuka Ueki, Erica Chimara

J Bras Pneumol.2008;34(8):590-594

Tuberculosis treatment: integration between hospitals and public health care clinics in the city of São Paulo, Brazil

Tratamento de tuberculose: integração entre assistência hospitalar e rede básica na cidade de São Paulo

Mirtes Cristina Telles Perrechi, Sandra Aparecida Ribeiro

J Bras Pneumol.2009;35(11):1100-1106

Analysis of treatment outcomes related to the tuberculosis control program in the city of Campinas, in the state of São Paulo, Brazil

Análise do programa de controle da tuberculose em relação ao tratamento, em Campinas - SP

Helenice Bosco de Oliveira, Leticia Marin-León, Jovana Gardinali

J Bras Pneumol.2005;31(2):133-138

Background: Tuberculosis cure is dependent upon treatment adherence. Objective: To analyze the results of tuberculosis treatment in public health clinics in the city of Campinas, in the state of São Paulo, Brazil, during 2002. Method: From a cohort of 484 patients diagnosed with tuberculosis, we evaluated 436. Treatment outcomes were described for all patients, whether new patients or patients in retreatment, including those presenting the pulmonary form, with or without acquired immunodeficiency syndrome (AIDS) comorbidity. Results: The success rate was 68.6% (72.3% among non-AIDS patients and 57.6% among AIDS patients). Among new cases, the non-AIDS group presented a 2.2-times greater chance of presenting favorable results. In the AIDS group, no differences were observed between new patients and those in retreatment. Among the unfavorable outcomes, only lethality presented a difference (18.9% among AIDS patients and 8.0% among non-AIDS patients). In patients presenting the pulmonary form, the success rate was similar between those who were initially acid-fast bacilli positive and those who were not. Conclusion: The tuberculosis control program in Campinas presented low effectiveness. In comparison to the 2001 national cohort, success rates were higher for non-AIDS patients but lower for AIDS patients. The higher success rate among cases of tuberculosis without AIDS was primarily derived from the treatment of new cases. The unfavorable profile of tuberculosis patients co-infected with AIDS, characterized by the (18.9%) lethality and the (15.3%) noncompliance, were partially responsible for the lower success rate seen among such patients. It is notable that such high proportions of noncompliant patients were seen in a city providing easy access to treatment. In order to improve the program, medical teams should receive further training in supervised treatment, health education and techniques for interacting with patients, all of which will require considerable investment.

Keywords: Key words: Tuberculosis. Treatment Refusal. Retreatment. Acquired Immunodeficiency Syndrome. Comorbidity

Factors associated with death by tuberculosis in the eastern part of São Paulo city, 2001

Fatores associados ao óbito por tuberculose na zona leste da cidade de São Paulo, 2001

Monica Hid Haddad Pelaquin, Rebeca Souza e Silva, Sandra Aparecida Ribeiro

J Bras Pneumol.2007;33(3):311-317

Editorial

Bringing the JBP and its readers closer together

O JBP mais próximo do leitor

Rogério Souza1

J Bras Pneumol.2015;41(3):209-210

Original Article

Epidemiological aspects of pleural tuberculosis in the state of São Paulo, Brazil (1998-2005)

Aspectos epidemiológicos da tuberculose pleural no estado de São Paulo (1998-2005)

Márcia Seiscento, Francisco Suso Vargas, Maria Josefa Penon Rujula, Sidney Bombarda, David Everson Uip, Vera Maria Nedes Galesi

J Bras Pneumol.2009;35(6):548-554

Symptom variability over the course of the day in patients with stable COPD in Brazil: a real-world observational study

Variabilidade dos sintomas diários de pacientes com DPOC estável no Brasil: um estudo observacional de vida real

Alberto Cukier1, Irma de Godoy2, Claudia Henrique da Costa3, Adalberto Sperb Rubin4, Marcelo Gervilla Gregorio5, Aldo Agra de Albuquerque Neto6, Marina Andrade Lima7, Monica Corso Pereira8, Suzana Erico Tanni2, Rodrigo Abensur Athanazio1, Elizabeth Jauhar Cardoso Bessa3, Fernando Cesar Wehrmeister9, Cristina Bassi Lourenco10, Ana Maria Baptista Menezes9

J Bras Pneumol.2020;46(3):e20190223

Effects of air temperature on the risk of death from COPD in major microregions in Brazil: a time series study

Efeitos da temperatura do ar no risco de morte por DPOC nas principais microrregiões do Brasil: um estudo de séries temporais

Igor Magaton Ribas1, João Pedro Medeiros Gomes¹, Pedro Augusto Rosa Valadares¹, Lucas Santos Jardim¹, Mário Círio Nogueira¹, Cássia de Castro Martins Ferreira2, William Cossich Marcial de Farias3, Letícia de Castro Martins Ferreira1

J Bras Pneumol.2023;49(5):e20220442

Lung donor profile in the state of São Paulo, Brazil, in 2006

Perfil do doador de pulmão disponibilizado no estado de São Paulo, Brasil, em 2006

Paulo Manuel Pêgo Fernandes, Marcos Naoyuki Samano, Jader Joel Machado Junqueira,Daniel Reis Waisberg, Gustavo Sousa Noleto, Fabio Biscegli Jatene

J Bras Pneumol.2008;34(7):497-505

Adverse effects of tuberculosis treatment: experience at an outpatient clinic of a teaching hospital in the city of São Paulo, Brazi

Efeitos adversos no tratamento da tuberculose: experiência em serviço ambulatorial de um hospital-escola na cidade de São Paulo

Denise Eri Onodera Vieira, Mauro Gomes

J Bras Pneumol.2008;34(12):1049-1055

Letters to the Editor

Tuberculosis in elderly patients in the city of Cali, Colombia: a hospital-based cohort study

Tuberculose em pacientes idosos na cidade de Cali, na Colômbia: um estudo de coorte de base hospitalar

Jose Fernando García-Goez1,2, Juan Diego Vélez1,2, Barbara Lucía Mora3, Luis Gabriel Parra-Lara2,3, Jessica Pino-Escobar3, Joan Artur Caylà4, Jose M. Miro5

J Bras Pneumol.2020;46(5):e20200072

Original Article

Prevalence of pectus carinatum and pectus excavatum in students in the city of Manaus, Brazil

Prevalência de pectus carinatum e pectus excavatum em escolares de Manaus

Fernando Luiz Westphal, Luiz Carlos de Lima, José Corrêia Lima Neto, Altair Rodrigues Chaves, Vítor Lazarini dos Santos Júnior, Brena Luize Cunha Ferreira

J Bras Pneumol.2009;35(3):221-226

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