Original Article

Pleural tuberculosis in the state of Roraima, Brazil, between 2005 and 2013: quality of diagnosis

Tuberculose pleural no estado de Roraima no período de 2005-2013: qualidade diagnóstica

Tao Machado1, Allex Jardim da Fonseca2, Sandra Maria Franco Buenafuente2

J Bras Pneumol.2016;42(2):106-113

Epidemiological aspects of pleural tuberculosis in the state of São Paulo, Brazil (1998-2005)

Aspectos epidemiológicos da tuberculose pleural no estado de São Paulo (1998-2005)

Márcia Seiscento, Francisco Suso Vargas, Maria Josefa Penon Rujula, Sidney Bombarda, David Everson Uip, Vera Maria Nedes Galesi

J Bras Pneumol.2009;35(6):548-554

Deaths attributed to multiple causes and involving tuberculosis in the state of Rio de Janeiro Brazil between 1999 and 2001

Causas múltiplas de morte relacionadas à tuberculose no Estado do Rio de Janeiro entre 1999 e 2001

Augusto Hasiak Santo

J Bras Pneumol.2006;32(6):544-552

Factors associated with delayed diagnosis of pulmonary tuberculosis in the state of Rio de Janeiro, Brazil

Fatores associados ao atraso no diagnóstico da tuberculose pulmonar no estado do Rio de Janeiro

Audry Cristina de Fátima Teixeira Machado, Ricardo Ewbank Steffen, Olivia Oxlade, Dick Menzies, Afrânio Kritski, Anete Trajman

J Bras Pneumol.2011;37(4):512-520

Scoring system for the diagnosis of tuberculosis in indigenous children and adolescents under 15 years of age in the state of Mato Grosso do Sul, Brazil

Diagnóstico da tuberculose em indígenas menores de quinze anos por meio de um sistema de pontuação em Mato Grosso do Sul

Sandra Christo dos Santos, Ana Maria Campos Marques, Roselene Lopes de Oliveira, Rivaldo Venâncio da Cunha

J Bras Pneumol.2013;39(1):84-91

Analysis of different primers used in the PCR method: diagnosis of tuberculosis in the state of Amazonas, Brazil

Análise de diferentes primers utilizados na PCR visando ao diagnóstico da tuberculose no Estado do Amazonas

Mauricio Morishi Ogusku, Julia Ignez Salem

J Bras Pneumol.2004;30(4):433-439

Efficiency of clinical, radiological and laboratory testing in the diagnosis of pleural tuberculosis

Rendimento de variáveis clínicas, radiológicas e laboratoriais para o diagnóstico da tuberculose pleural

Denise Duprat Neves, Ricardo Marques Dias, Antônio José Ledo Alves da Cunha, Antonio Monteiro da Silva Chibante

J Bras Pneumol.2004;30(4):409-416

Relationship between the magnitude of symptoms and the quality of life:a cluster analysis of lung cancer patients in Brazil

Relação entre a magnitude de sintomas e a qualidade de vida: análise de agrupamentos depacientes com câncer de pulmão no Brasil

Juliana Franceschini, José Roberto Jardim, Ana Luisa Godoy Fernandes,Sérgio Jamnik, Ilka Lopes Santoro

J Bras Pneumol.2013;39(1):23-31

Brief Communication

Temporal trends in tuberculosis-related morbidity and mortality in the state of Santa Catarina, Brazil, between 2002 and 2009

Tendência temporal da morbidade e mortalidade por tuberculose no estado de Santa Catarina, Brasil, no período entre 2002 e 2009

Jefferson Traebert, Glênio César Nunes Ferrer, Nazaré Otília Nazário, Ione Jayce Ceola Schneider, Rosemeri Maurici da Silva

J Bras Pneumol.2012;38(6):757-760

Tuberculosis and gender in a priority city in the state of Rio de Janeiro, Brazil

Tuberculose e gênero em um município prioritário no estado do Rio de Janeiro

Márcia Teresa Carreira Teixeira Belo, Ronir Ragio Luiz, Christy Hanson, Lia Selig, Eleny Guimarães Teixeira, Thiago Chalfoun, Anete Trajman

J Bras Pneumol.2010;36(5):621-625

Original Article

Relationship between home environmental control and exacerbation of asthma in children and adolescents in the city of Camaragibe in the state of Pernambuco, Brazil

Associação entre controle ambiental domiciliar e exacerbação da asma em crianças e adolescentes do município de Camaragibe, Pernambuco*

Rosane M. Barreto de Melo, Luciane S. de Lima, Emanuel S.Cavalcanti Sarinho

J Bras Pneumol.2005;31(1):5-15

Nontuberculous mycobacteria isolated in São José do Rio Preto, Brazil between 1996 and 2005

Isolamento de micobactérias não-tuberculosas em São José do Rio Preto entre 1996 e 2005

Heloisa da Silveira Paro Pedro, Maria Izabel Ferreira Pereira, Maria do Rosário Assad Goloni, Suely Yoko Mizuka Ueki, Erica Chimara

J Bras Pneumol.2008;34(11):950-955

Performance of the quantification of adenosine deaminase and determination of the lactate dehydrogenase/adenosine deaminase ratio for the diagnosis of pleural tuberculosis in children and adolescents

Desempenho da quantificação de adenosina desaminase e determinação da relação lactato desidrogenase/adenosina desaminase para o diagnóstico de tuberculose pleural em crianças e adolescentes

Julia Lima Vieira1, Luiza Foschiera1, Isabel Cristina Schutz Ferreira1, Valentina Coutinho Baldoto Gava Chakr1,2

J Bras Pneumol.2021;47(2):e20200558

Evaluation of adenosine deaminase in the diagnosis of pleural tuberculosis: a Brazilian meta-analysis

Avaliação da adenosina desaminase no diagnóstico da tuberculose pleural: uma metanálise brasileira

Patrizio Morisson, Denise Duprat Neves

J Bras Pneumol.2008;34(4):217-224

Evaluation of surveillance of contacts of new tuberculosis cases in the state of Mato Grosso - Brazil

Avaliação da vigilância de contatos de casos novos de tuberculose no Estado de Mato Grosso - Brasil

Shaiana Vilella Hartwig, Eliane Ignotti, Beatriz Fátima Alves de Oliveira, Hellen Caroline de Oliveira Pereira, João Henrique Scatena

J Bras Pneumol.2008;34(5):298-303

The burden of disease due to tuberculosis in the state of Santa Catarina, Brazil

A carga de doença por tuberculose no estado de Santa Catarina

J Bras Pneumol.2014;40(1):61-68

Impact of multiple biopsies in two different sites of the pleural surface for the diagnosis of tuberculosis

Impacto de múltiplas biópsias em dois pontos distintos da superfície pleural no diagnóstico de tuberculose

Marcelo Chalhoub, Ronald Fidelis, Ana Paula Barreto, Eduardo Ramos, Manoel Barral-Netto, Aryon Almeida Barbosa Jr.

J Bras Pneumol.2000;26(2):55-60

For diagnostic purposes of pleural tuberculosis, three pleural fragments are routinely obtained from a single site by needle biopsy. The objective of this study is to compare the diagnostic yield of the routine procedure with two different approaches: harvesting five fragments on a single site (A), and collection of fragments at an additional site (B); from the same cutaneous orifice, the needle was partially removed up to the subcutaneous tissue and redirected at a 45o angle. The authors performed a prospective study in 115 patients submitted to pleural biopsy. The first three pleural fragments were placed in a vial (VA1-3), the 5 subsequent fragments obtained at the same site were placed in a second vial (VA4-8), and the five fragments from the second site were placed in a third vial (VB1-5). Analysis of fragments from VA1-3 revealed granuloma in 72/92 tuberculosis cases (78.3%), whereas in fragments VA5-8 and VB1-5, granuloma was observed in 74/92 cases (80.5%). In 6/92 patients the diagnosis at VA1-3 was non-specific pleuritis, but granuloma was found in VA4-8, resulting in a diagnosis increment of 8.3% (adding six to the 72 patients). In 7/92 patients (7.6%) the histopathological examination at site A led to a non-specific result but granuloma was found at site B, leading to a diagnostic increment of 9.0% (7 to 78 patients). Histological concordance of two examinations by the same pathologist had a kappa index of 0.62 (0.54 to 0.7) whereas concordance between two different pathologists had a kappa index of 0.64 (0.56 to 0.72). The performance of multiple biopsies at two different sites at the pleural surface led to an additional diagnosis of 13 patients, i.e., an increase of 18% (13 to 72) relative to the routine procedure. Considering the low cost increase of obtaining the fragments, adoption of this method is recommended in routine pleural tuberculosis diagnosis.

Keywords: Tuberculosis, pleural tuberculosis, biopsy, diagnosis.