Original Article

Silicosis among PIT diggers in the region of Ibiapaba, State of Ceará, Brazil: from detection to control

Silicose em cavadores de poços da região de Ibiapaba (CE): da descoberta ao controle

Márcia Alcântara Holanda, Ana Carolina Peixoto do Rego Barros, Alexandre Alcântara Holanda, Cristina Gomes do Monte, Elias Bezerra Leite, Luiz Ximenes Junior, Maria Zélia Maia Holanda, Pedro Henrique Felismino

J Bras Pneumol.1999;25(1):1-11

Case Report

Pulmonary and extrapulmonary coccidioidomycosis: three cases in an endemic area in the state of Ceará, Brazil

Coccidioidomicose pulmonar e extrapulmonar: três casos em zona endêmica no interior do Ceará

Ricardo Hideo Togashi, Fernando Moreira Batista Aguiar, Dalton Barros Ferreira, Camille Matos de Moura, Monique Teixeira Montezuma Sales, Nikaelle Ximenes Rios

J Bras Pneumol.2009;35(3):275-279

Original Article

Descriptive study of the frequency of nontuberculous mycobacteria in the Baixada Santista region of the state of São Paulo, Brazil

Estudo descritivo da freqüência de micobactérias não tuberculosas na Baixada Santista

Liliana Aparecida Zamarioli, Andréa Gobetti Vieira Coelho, Clemira Martins Pereira, Ana Carolina Chiou Nascimento, Suely Yoko Mizuka Ueki, Erica Chimara

J Bras Pneumol.2008;34(8):590-594

Outpatient smoking cessation program in the state of Ceará, Brazil: patient profiles and factors associated with treatment success

Ambulatório de apoio ao tabagista no Ceará: perfil dos pacientes e fatores associados ao sucesso terapêutico

Maria Penha Uchoa Sales, Mara Rúbia Fernandes de Figueiredo, Maria Irenilza de Oliveira, Helano Neiva de Castro

J Bras Pneumol.2006;32(5):410-417

Prevalence of and factors related to tuberculosis in seropositive human immunodeficiency virus patients at a reference center for treatment of human immunodeficiency virus in the southern region of the state of Rio Grande do Sul, Brazil

Prevalência e fatores associados à tuberculose em pacientes soropositivos para o vírus da imunodeficiência humana em centro de referência para tratamento da síndrome da imunodeficiência adquirida na região sul do Rio Grande do Sul

Jussara Maria Silveira, Raúl Andrés Mendoza Sassi, Isabel Cristina de Oliveira Netto, Jorge Lima Hetzel

J Bras Pneumol.2006;32(1):48-55

Objective: In view of the relevance of co-infection with tuberculosis and human immunodeficiency virus, this study was designed to determine tuberculosis prevalence and identify factors related to tuberculosis in patients residing in a region in which both infections are highly prevalent. Methods: All patients treated during 1999 at the HIV/AIDS Clinic of the Universidade Federal do Rio Grande (Rio Grande Federal University) University Hospital were evaluated retrospectively, from the time of human immunodeficiency virus diagnosis, in terms of the incidence of tuberculosis and its relationship to sociodemographic, behavioral and immunological factors. Results: The sample included 204 patients, and tuberculosis prevalence was found to be 27%. The multivariate analysis showed a significant correlation between the development of tuberculosis and being of African descent (odds ratio: 4.76; 95% confidence interval: 1.93-11.72) and an inverse correlation between the development of tuberculosis and the TCD4+ lymphocyte count at the time of human immunodeficiency virus diagnosis (odds ratio: 0.995; 95% confidence interval: 0.993-0.997). When analyzed separately, other variables were found to be potential risk factors: being of the male gender (odds ratio: 2.49; 95% confidence interval: 1.15-5.39); and using illicit drugs (odds ratio: 2.1; 95% confidence interval: 1.02-4.31). Conclusion: The factors responsible for the development of tuberculosis among patients who are human immunodeficiency virus seropositive include immunological, socioeconomic and demographic factors. The high rate of tuberculosis prevalence among the seropositive patients underscores the urgent need to implement strategies that combine rapid identification and prompt treatment of individuals with active or latent infection, as well as of those with whom they have been in contact.

Keywords: HIV Infections/complications; AIDS-related opportunistic infections/complications; Tuberculosis/etiology; Tuberculosis/epidemiology

Analysis of treatment outcomes related to the tuberculosis control program in the city of Campinas, in the state of São Paulo, Brazil

Análise do programa de controle da tuberculose em relação ao tratamento, em Campinas - SP

Helenice Bosco de Oliveira, Leticia Marin-León, Jovana Gardinali

J Bras Pneumol.2005;31(2):133-138

Background: Tuberculosis cure is dependent upon treatment adherence. Objective: To analyze the results of tuberculosis treatment in public health clinics in the city of Campinas, in the state of São Paulo, Brazil, during 2002. Method: From a cohort of 484 patients diagnosed with tuberculosis, we evaluated 436. Treatment outcomes were described for all patients, whether new patients or patients in retreatment, including those presenting the pulmonary form, with or without acquired immunodeficiency syndrome (AIDS) comorbidity. Results: The success rate was 68.6% (72.3% among non-AIDS patients and 57.6% among AIDS patients). Among new cases, the non-AIDS group presented a 2.2-times greater chance of presenting favorable results. In the AIDS group, no differences were observed between new patients and those in retreatment. Among the unfavorable outcomes, only lethality presented a difference (18.9% among AIDS patients and 8.0% among non-AIDS patients). In patients presenting the pulmonary form, the success rate was similar between those who were initially acid-fast bacilli positive and those who were not. Conclusion: The tuberculosis control program in Campinas presented low effectiveness. In comparison to the 2001 national cohort, success rates were higher for non-AIDS patients but lower for AIDS patients. The higher success rate among cases of tuberculosis without AIDS was primarily derived from the treatment of new cases. The unfavorable profile of tuberculosis patients co-infected with AIDS, characterized by the (18.9%) lethality and the (15.3%) noncompliance, were partially responsible for the lower success rate seen among such patients. It is notable that such high proportions of noncompliant patients were seen in a city providing easy access to treatment. In order to improve the program, medical teams should receive further training in supervised treatment, health education and techniques for interacting with patients, all of which will require considerable investment.

Keywords: Key words: Tuberculosis. Treatment Refusal. Retreatment. Acquired Immunodeficiency Syndrome. Comorbidity

Smoking among physicians in a specific region of the greater metropolitan area of São Paulo

Tabagismo entre médicos da Região do ABC Paulista

Adriano Cesar Guazzelli, Mário Terra Filho, Elie Fiss

J Bras Pneumol.2005;31(6):516-522

Genetic polymorphisms and their effects on the severity of silicosis in workers exposed to silica in Brazil

Polimorfismos genéticos e seus efeitos na gravidade da silicose em trabalhadores expostos à sílica no Brasil

Marcos César Santos de Castro1,2,3, Angela Santos Ferreira Nani2, Kaio Cezar Rodrigues Salum1, Jônatas de Mendonça Rolando1, Júlia Fernandes Barbosa dos Santos1, Hermano Albuquerque de Castro4, Patrícia Canto Ribeiro4, Walter Costa3, Cícero Brasileiro de Mello1,5, Fabiana Barzotto Kohlrausch5

J Bras Pneumol.2022;48(5):e20220167

Prevalence of smoking among adults residing in the Federal District of Brasília and in the state capitals of Brazil, 2008

Prevalência do tabagismo em adultos residentes nas capitais dos estados e no Distrito Federal, Brasil, 2008

Deborah Carvalho Malta, Erly Catarina Moura, Sara Araújo Silva, Patrícia Pereira Vasconcelos de Oliveira, Vera Luiza da Costa e Silva

J Bras Pneumol.2010;36(1):75-83

Multidrug-resistant tuberculosis prevalence in Ceará State - Northeastern Brazil, 1990-1999

Prevalência da tuberculose multirresistente no Estado do Ceará, 1990-1999*

Elizabeth Clara Barroso, Jorge Luís Nobre Rodrigues, Valéria Góes Ferreira Pinheiro, Creuza L. Campelo

J Bras Pneumol.2001;27(6):310-314

Brief Communication

Evaluation of the nitrate reductase assay for the rapid detection of resistance to first-line medications in Mycobacterium tuberculosis strains isolated from patients in a general hospital

Avaliação do teste de nitrato redutase para a detecção rápida de resistência aos medicamentos de primeira linha em cepas de Mycobacterium tuberculosis isoladas de pacientes em um hospital geral

Maria de Fátima Filardi Oliveira Mansur, Wânia da Silva Carvalho, Raquel Bandeira da Silva, Rodrigo Gonçalves Cata Preta, Lucas Almeida Fernandes Junior, Silvana Spíndola de Miranda

J Bras Pneumol.2012;38(2):210-213

Original Article

Asthma morbidity and mortality in the State of Parana and in city of Curitiba from 1984 to 1995

Morbimortalidade por asma no Estado do Paraná e município de Curitiba no período entre 1984 e 1995

Sônia Zulato, Denise Carvalho, Anne-Claire Ribeiro, Nelson Augusto Rosário Filho

J Bras Pneumol.1999;25(1):12-16

The burden of disease due to tuberculosis in the state of Santa Catarina, Brazil

A carga de doença por tuberculose no estado de Santa Catarina

J Bras Pneumol.2014;40(1):61-68

Spatial analysis of hospitalizations for pneumonia in the Vale do Paraíba region of Brazil

Análise espacial das internações por pneumonia na região do Vale do Paraíba (SP)

Adriana de Oliveira Mukai, Kátia de Souza Costa Alves, Luiz Fernando Costa Nascimento

J Bras Pneumol.2009;35(8):753-758

Completeness of tuberculosis control program records in the case registry database of the state of Espírito Santo, Brazil: analysis of the 2001-2005 period

Completude dos dados do Programa de Controle da Tuberculose no Sistema de Informação de Agravos de Notificação no Estado do Espírito Santo, Brasil: uma análise do período de 2001 a 2005

Cláudia Maria Marques Moreira, Ethel Leonor Noia Maciel

J Bras Pneumol.2008;34(4):225-229

Evolution of public policies and programs for asthma control in Brazil from the perspective of consensus guidelines

Evolução das políticas públicas e programas de controle da asma no Brasil sob a perspectiva dos consensos

Ligia Menezes do Amaral, Pamella Valente Palma, Isabel Cristina Gonçalves Leite

J Bras Pneumol.2012;38(4):518-525

Relationship between home environmental control and exacerbation of asthma in children and adolescents in the city of Camaragibe in the state of Pernambuco, Brazil

Associação entre controle ambiental domiciliar e exacerbação da asma em crianças e adolescentes do município de Camaragibe, Pernambuco*

Rosane M. Barreto de Melo, Luciane S. de Lima, Emanuel S.Cavalcanti Sarinho

J Bras Pneumol.2005;31(1):5-15

Mortality due to idiopathic pulmonary fibrosis in the State of Rio Grande do Sul (Brazil)

Mortalidade por fibrose pulmonar idiopática no Rio Grande do Sul

Fabrício Picolli Fortuna, Christiano Perin, Letícia Cunha, Adalberto Sperb Rubin

J Bras Pneumol.2003;29(3):121-124

Correspondence

Open letter to city, state, and federal health authorities, to State Health Councils, and to the National Council of Municipal Health Secretaries in Brazil

Carta aberta às autoridades federais, estaduais e municipais do setor da saúde, aos Conselhos Estaduais de Saúde e ao Conselho Nacional dos Secretários Municipais de Saúde

J Bras Pneumol.2016;42(2):160

Original Article

Characteristics of elderly tuberculosis patients in Recife, Brazil: a contribution to the tuberculosis control program

Características da tuberculose em idosos no Recife (PE): contribuição para o programa de controle

Zilda do Rego Cavalcanti, Maria de Fátima Pessoa Militão de Albuquerque, Antônio Roberto Leite Campelo, Ricardo Ximenes, Ulisses Montarroyos, Marianne Karel Amaral Verçosa

J Bras Pneumol.2006;32(6):535-543

Objective: To describe the demographic characteristics, everyday habits, socio-economic conditions, clinico-epidemiological profiles and access to health care services among the elderly patients with tuberculosis diagnosed and treated in the city of Recife, Brazil, comparing them to those observed in young adults with tuberculosis. Methods: A case-control type strategy was used to evaluate a cohort of patients with tuberculosis, all of whom were treated in public health care facilities in Recife between May of 2001 and July of 2003. Results: The final cohort consisted of 1127 patients: 136 elderly patients (cases) and 991 young adults (controls). In both groups, males predominated, and the most common form of tuberculosis was the pulmonary form. Alcoholism was more common in the control group, whereas illiteracy was more common in the case group. There were fewer complaints of cough, sweats and chest pain among the patients in the case group than among those in the control group. Serological testing for the human immunodeficiency virus was performed in only 29 patients (2.6%). The percentage of positive sputum smear microscopy results, as well as that of positive cultures, was higher in the controls. Prior to being diagnosed with the disease, patients in both groups had sought treatment at more than two health care facilities and had waited more than two months (after first seeking treatment). The elderly patients presented higher indices of cure and were more often compliant with the treatment regimen, yet presented higher mortality rates. Conclusion: In the population studied, the elderly presented less cough, fewer episodes of night sweats and less chest pain, as well as less often presenting positivity on complementary exams. Nevertheless, the mortality rate was higher among the elderly patients than among the young adult patients. Elderly patients with tuberculosis constitute a population that should be given special attention in public health care facilities.

Keywords: Tuberculosis; Elderly; Case-control; Brazil

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