Original Article

Effects of air temperature on the risk of death from COPD in major microregions in Brazil: a time series study

Efeitos da temperatura do ar no risco de morte por DPOC nas principais microrregiões do Brasil: um estudo de séries temporais

Igor Magaton Ribas1, João Pedro Medeiros Gomes¹, Pedro Augusto Rosa Valadares¹, Lucas Santos Jardim¹, Mário Círio Nogueira¹, Cássia de Castro Martins Ferreira2, William Cossich Marcial de Farias3, Letícia de Castro Martins Ferreira1

J Bras Pneumol.2023;49(5):e20220442

Random sample survey on the prevalence of smoking in the major cities of Brazil

Levantamento randomizado sobre a prevalência de tabagismo nos maiores municípios do Brasil

Fernando Sergio Leitão Filho, José Carlos Fernandes Galduróz, Ana Regina Noto, Solange Aparecida Nappo, Elisaldo Araújo Carlini, Oliver Augusto Nascimento, Sérgio Ricardo Santos, José Roberto Jardim

J Bras Pneumol.2009;35(12):

Anthropometric status of individuals with COPD in the city of São Paulo, Brazil, over time - analysis of a population-based study

Análise evolutiva antropométrica em indivíduos com DPOC na cidade de São Paulo - estudo de base populacional

Josiane Marchioro1,a, Mariana Rodrigues Gazzotti1,b, Graciane Laender Moreira1,c, Beatriz Martins Manzano1,d, Ana Maria Baptista Menezes2,e, Rogélio Perez-Padilla3,f, José Roberto Jardim1,g, Oliver Augusto Nascimento1,4,h, PLATINO Team

J Bras Pneumol.2019;45(6):e20170157

Brain death effects on lung microvasculature in an experimental model of lung donor

Efeitos da morte cerebral na microvasculatura pulmonar em um modelo experimental de doador de pulmão

Rafael Simas1, Fernando Luiz Zanoni1, Raphael dos Santos Coutinho e Silva1, Luiz Felipe Pinho Moreira1

J Bras Pneumol.2020;46(2):e20180299

Determinants of death in critically ill COVID-19 patients during the first wave of COVID-19: a multicenter study in Brazil

Determinantes de mortalidade em pacientes com COVID-19 em estado crítico durante a primeira onda da doença: estudo multicêntrico no Brasil

Fernando Jose da Silva Ramos1,2, Fernanda Chohfi Atallah1,2, Maria Aparecida de Souza1, Elaine Maria Ferreira1, Flavia Ribeiro Machado1, Flavio Geraldo Resende Freitas1,3

J Bras Pneumol.2022;48(5):e20220083

Hospitalizations for pulmonary embolism in Brazil (2008-2019): an ecological and time series study

Hospitalizações por embolia pulmonar no Brasil (2008-2019): um estudo ecológico e de séries temporais

Jéssica Alves Gomes1, José Elias Bezerra Barros1, André Luis Oliveira do Nascimento1, Carlos Alberto de Oliveira Rocha1, João Paulo Oliveira de Almeida1, Gibson Barros de Almeida Santana1, Divanise Suruagy Correia2, Márcio Bezerra Santos3, Rodrigo Feliciano do Carmo4,5, Carlos Dornels Freire de Souza1,6

J Bras Pneumol.2022;48(3):e20210434

Cystic fibrosis-related mortality trends in Brazil for the 1999-2017 period: a multiple-cause-of-death study

Tendências de mortalidade relacionada à fibrose cística no Brasil no período de 1999 a 2017: um estudo de causas múltiplas de morte

Augusto Hasiak Santo1a, Luiz Vicente Ribeiro Ferreira da Silva-Filho2,3a

J Bras Pneumol.2021;47(2):e20200166

Effects of indacaterol versus tiotropium on exercise tolerance in patients with moderate COPD: a pilot randomized crossover study

Efeitos do indacaterol versus tiotrópio na tolerância ao exercício em pacientes com DPOC moderada: estudo cruzado randomizado piloto

Danilo Cortozi Berton1, Álvaro Huber dos Santos2, Ivo Bohn Jr.2, Rodrigo Quevedo de Lima2, Vanderléia Breda2, Paulo José Zimermann Teixeira2,3,4

J Bras Pneumol.2016;42(5):362-366

Objective: To compare a once-daily long-acting β2 agonist (indacaterol 150 µg) with a once-daily long-acting anticholinergic (tiotropium 5 µg) in terms of their effects on exercise endurance (limit of tolerance, Tlim) in patients with moderate COPD. Secondary endpoints were their effects on lung hyperinflation, exercise-related dyspnea, and daily-life dyspnea. Methods: This was a randomized, single-blind, crossover pilot study involving 20 patients (mean age, 60.9 ± 10.0 years; mean FEV1, 69 ± 7% of predicted). Spirometric parameters, Transition Dyspnea Index scores, Tlim, and exertional dyspnea were compared after three weeks of each treatment (with a one-week washout period between treatments). Results: Nineteen patients completed the study (one having been excluded because of COPD exacerbation). Improvement in Tlim from baseline tended to be greater after treatment with tiotropium than after treatment with indacaterol (96 ± 163 s vs. 8 ± 82 s; p = 0.06). Tlim significantly improved from baseline after treatment with tiotropium (having increased from 396 ± 319 s to 493 ± 347 s; p = 0.010) but not after treatment with indacaterol (having increased from 393 ± 246 to 401 ± 254 s; p = 0.678). There were no differences between the two treatments regarding improvements in Borg dyspnea scores and lung hyperinflation at "isotime" and peak exercise. There were also no significant differences between treatments regarding Transition Dyspnea Index scores (1.5 ± 2.1 vs. 0.9 ± 2.3; p = 0.39). Conclusions: In patients with moderate COPD, tiotropium tends to improve Tlim in comparison with indacaterol. No significant differences were observed between the two treatments regarding their effects on lung hyperinflation, exercise-related dyspnea, and daily-life dyspnea. Future studies, including a larger number of patients, are required in order to confirm our findings and explore mechanistic explanations. (ClinicalTrials.gov identifier: NCT01693003 [http://www.clinicaltrials.gov/])

Keywords: Pulmonary disease, chronic obstructive; Exercise; Bronchodilator agents.

Effects of the implementation of a hand hygiene education program among ICU professionals: an interrupted time-series analysis

Efeitos da implementação de um programa de educação de higienização das mãos entre profissionais de uma UTI: análise de séries temporais interrompidas

Diana Marcela Prieto Romero1,a, Maycon Moura Reboredo1,2,b, Edimar Pedrosa Gomes1,2,c, Cristina Martins Coelho1,d, Maria Aparecida Stroppa de Paula1,e, Luciene Carnevale de Souza1,f, Fernando Antonio Basile Colugnati2,g, Bruno Valle Pinheiro1,2,hDiana Marcela Prieto Romero1,a, Maycon Moura Reboredo1,2,b, Edimar Pedrosa Gomes1,2,c, Cristina Martins Coelho1,d, Maria Aparecida Stroppa de Paula1,e, Luciene Carnevale de Souza1,f, Fernando Antonio Basile Colugnati2,g, Bruno Valle Pinheiro1,2,h

J Bras Pneumol.2019;45(5):e20180152

Letters to the Editor

Short-term effects of elexacaftor/tezacaftor/ivacaftor in pediatric cystic fibrosis patients in Brazil: a case series

Marta Amor Barbosa1, Fernanda Maria Vendrusculo2, Matias Epifanio2, Marcio Vinicius Fagundes Donadio1,2, Leonardo Araujo Pinto2

J Bras Pneumol.2024;50(5):e20230403

Original Article

Overprescription of short-acting β2 agonists: reflections from the SABINA study in Brazil

Prescrição excessiva de β2-agonistas de curta duração: reflexões a partir do estudo SABINA no Brasil

Martti Anton Antila1, Adelmir Souza-Machado2,4, Marcelo Gervilla Gregório3, Álvaro A Cruz4,5, Luciene Angelini6, Maarten J H I Beekman7, Gilmar Alves Zonzin8, Marcelo Fouad Rabahi9

J Bras Pneumol.2024;50(1):e20230174

Effects of expiratory positive airway pressure on the electromyographic activity of accessory inspiratory muscles in COPD patients

Efeitos da pressão positiva expiratória nas vias aéreas sobre a atividade eletromiográfica da musculatura acessória da inspiração em portadores de DPOC

Dannuey Machado Cardoso, Dulciane Nunes Paiva, Isabella Martins de Albuquerque, Renan Trevisan Jost, Andréia Vanessa da Paixão

J Bras Pneumol.2011;37(1):46-53

Effects of varenicline on lung tissue in the animal model

Efeitos da vareniclina no tecido pulmonar em modelo animal

Hilal Ermis1, Hakan Parlakpinar2, Hulya Elbe3, Nigar Vardi4, Alaaddin Polat5, Gazi Gulbas1

J Bras Pneumol.2020;46(2):e20180406

PLATINO, a nine-year follow-up study of COPD in the city of São Paulo, Brazil: the problem of underdiagnosis

PLATINO, estudo de seguimento de nove anos sobre DPOC na cidade de São Paulo: o problema do subdiagnóstico

J Bras Pneumol.2014;40(1):30-37

Objective: To determine the underdiagnosis rate in new COPD cases at the end of a nine-year follow-up period-in the study designated "Projeto Latino-Americano de Investigação em Obstrução Pulmonar" (PLATINO, Latin-American Pulmonary Obstruction Investigation Project)-and compare that with the underdiagnosis rate during the initial phase of the study, as well as to identify the clinical features exhibited by the subjects who were not diagnosed until the end of the follow-up phase. Methods: The study population comprised the 1,000 residents of the city of São Paulo, Brazil, who took part in the PLATINO study. Of those, 613 participated in the follow-up phase, during which the subjects were assessed with the same instruments and equipment employed in the initial phase of the study. We used the chi-square test or the independent sample t-test to analyze the underdiagnosis rate and to identify the characteristics of the subjects who were not diagnosed until the end of the follow-up phase. Results: The underdiagnosis rate for new COPD cases at the end of the nine-year follow-up period was 70.0%. The underdiagnosis rate during the follow-up phase was 17.5% lower than that reported for the initial phase of the study. The subjects who were not diagnosed until the end of the follow-up phase presented with fewer respiratory symptoms, better pulmonary function, and less severe disease than did those previously diagnosed with COPD. Conclusions: The underdiagnosis rate for new COPD cases was lower in the follow-up phase of the study than in the initial phase. The subjects who were not diagnosed until the end of the follow-up phase of the PLATINO study presented with the same clinical profile as did those who were not diagnosed in the initial phase. These findings underscore the need for spirometry in order to confirm the diagnosis of COPD and provide early intervention.

Keywords: Pulmonary disease, chronic obstructive/diagnosis; Pulmonary disease, chronic obstructive/epidemiology; Spirometry.

Genetic polymorphisms and their effects on the severity of silicosis in workers exposed to silica in Brazil

Polimorfismos genéticos e seus efeitos na gravidade da silicose em trabalhadores expostos à sílica no Brasil

Marcos César Santos de Castro1,2,3, Angela Santos Ferreira Nani2, Kaio Cezar Rodrigues Salum1, Jônatas de Mendonça Rolando1, Júlia Fernandes Barbosa dos Santos1, Hermano Albuquerque de Castro4, Patrícia Canto Ribeiro4, Walter Costa3, Cícero Brasileiro de Mello1,5, Fabiana Barzotto Kohlrausch5

J Bras Pneumol.2022;48(5):e20220167

Symptom variability over the course of the day in patients with stable COPD in Brazil: a real-world observational study

Variabilidade dos sintomas diários de pacientes com DPOC estável no Brasil: um estudo observacional de vida real

Alberto Cukier1, Irma de Godoy2, Claudia Henrique da Costa3, Adalberto Sperb Rubin4, Marcelo Gervilla Gregorio5, Aldo Agra de Albuquerque Neto6, Marina Andrade Lima7, Monica Corso Pereira8, Suzana Erico Tanni2, Rodrigo Abensur Athanazio1, Elizabeth Jauhar Cardoso Bessa3, Fernando Cesar Wehrmeister9, Cristina Bassi Lourenco10, Ana Maria Baptista Menezes9

J Bras Pneumol.2020;46(3):e20190223

Effects of emissions from sugar cane burning on the trachea and lungs of Wistar rats

Efeitos das emissões geradas pela queima da cana-de-açúcar em traqueia e pulmões de ratos Wistar

Verena Sampaio Barbosa Matos1, Felipe da Silva Gomes2, Tarcio Macena Oliveira2, Renata da Silva Schulz1, Lídia Cristina Villela Ribeiro3, Astria Dias Ferrão Gonzales3,4, Januário Mourão Lima4, Marcos Lázaro da Silva Guerreiro3,4

J Bras Pneumol.2017;43(3):208-214

Time from symptom onset to the initiation of treatment of pulmonary tuberculosis in a city with a high incidence of the disease

Tempo entre o início dos sintomas e o tratamento de tuberculose pulmonar em um município com elevada incidência da doença

Marina de Loureiro Maior, Renata Leborato Guerra, Michelle Cailleaux-Cezar, Jonathan Eric Golub, Marcus Barreto Conde

J Bras Pneumol.2012;38(2):202-209

Continuing Education: Respiratory Physiology

Uncovering the beneficial effects of inhaled bronchodilator in COPD: beyond forced spirometry

Revelando os efeitos benéficos do broncodilatador inalatório na DPOC: além da espirometria forçada

José Alberto Neder1,a, Danilo Cortozi Berton2,b, Denis E O'Donnell1,c

J Bras Pneumol.2019;45(3):e20190168

Search Results

Original Article

Letters to the Editor

Original Article

Continuing Education: Respiratory Physiology

Anos

Seções

Indexes

Official publication

Newsletters