Original Article

Alterations in peak inspiratory pressure and tidal volume delivered by manually operated self-inflating resuscitation bags as a function of the oxygen supply rate

Alterações da pressão de pico inspiratório e do volume corrente fornecidos por reanimadores manuais com balão auto-inflável em função do fluxo de entrada de oxigênio utilizado

Armando Carlos Franco de Godoy, Ronan José Vieira, Eduardo Mello De Capitani

J Bras Pneumol.2008;34(10):817-821

Oxygen outflow delivered by manually operated self-inflating resuscitation bags in patients breathing spontaneously

Fluxo de saída de oxigênio fornecido por reanimadores manuais com balão auto-inflável em pacientes com ventilação espontânea

Armando Carlos Franco de Godoy, Ronan José Vieira, Ronan José Vieira Neto

J Bras Pneumol.2008;34(4):212-216

Evaluation of manual resuscitators used in ICUs in Brazil

Avaliação de reanimadores manuais utilizados em UTIs brasileiras

Tatiana de Arruda Ortiz, Germano Forti Junior, Márcia Souza Volpe, Marcelo do Amaral Beraldo, Marcelo Britto Passos Amato, Carlos Roberto Ribeiro Carvalho, Mauro Roberto Tucci

J Bras Pneumol.2013;39(5):595-603

Volume controlled ventilation versus pressure controlled ventilation in a canine acute lung injury model: effects on cardiorespiratory parameters and oxygen cost of breathing

Ventilação mecânica volume-controlada versus pressão controlada em modelo canino de lesão pulmonar aguda: efeitos cardiorrespiratórios e sobre o custo de oxigênio da respiração

Bruno do Valle Pinheiro, Marcelo Alcântara Holanda, Célia Mallart Larges, Oswaldo Shigueomi Beppu

J Bras Pneumol.2002;28(1):15-22

Background: It is questionable whether pressure-controlled ventilation (PCV) has advantages over volume-cycled ventilation (VCV). Objectives: To compare PCV to VCV with decelerating flow profile during assisted and controlled modes in an acute lung injury experimental model. Methods: Severe acute lung injury (PaO2/FIO2 < 100 mmHg) was induced by oleic acid IV infusion (0.05 mg/kg) in seven dogs. The animals were submitted to PCV and VCV in a randomized sequence. After 40 minutes in the assisted mode, ventilation was changed to the controlled mode after neuromuscular blockade. The tidal volume and the inspiratory time were kept constant throughout the experiment. Results: There were no differences in gas exchange (PaO2 and PaCO2), cardiac output or oxygen delivery (DO2) between VCV and PCV. The same was observed regarding maximum airway and plateau pressures, and also to the static compliance. Oxygen consumption (VO2) after neuromuscular blockade was 124 ± 48 in VCV versus 143 ± 50 ml/min in PCV, p = 0.42. In the assisted mode, there was a statistical trend of a higher VO2 in PCV (219 ± 72 versus 154 ± 67 ml/min in VCV, p = 0.06), that was associated with a statistical trend of a higher oxygen cost of breathing (OCB) during assisted PCV, although without statistical significance (31 ± 77 in VCV versus 75 ± 96 ml/min in PCV, p = 0.23), and also in a lower PvO2 (34 ± 7 in PCV versus 42 ± 6 ml/min in VCV, p = 0.02). These occurred despite a higher maximum inspiratory flow in the assisted mode in PCV (58 ± 9 versus 48 ± 4 L/min in VCV, p = 0.01). In both VCV and PCV the institution of controlled ventilation reduced cardiac debit and DO2 in as much as 20% relative to the assisted mode. Conclusions: The implementation of controlled ventilation improved the oxygen delivery/consumption relationship in this severe and with high OCB acute lung injury model. The PCV offered no additional benefits to VCV and it was associated with a higher OCB during the assisted mode.

Keywords: Artificial respiration. Pulmonary gas exchange. Tidal volume.

Low tidal volume mechanical ventilation and oxidative stress in healthy mouse lungs

Ventilação mecânica com baixo volume corrente e estresse oxidativo em pulmões saudáveis de camundongos

Karla Maria Pereira Pires, Adriana Correa Melo, Manuella Lanzetti, Natália Vasconcelos Casquilho, Walter Araújo Zin, Luís Cristóvão Porto, Samuel Santos Valença

J Bras Pneumol.2012;38(1):98-104

Brief Communication

Noninvasive determination of inspiratory pressure in patients with spinal cord injury: what is the best method?

Determinação não-invasiva da pressão inspiratória em pacientes com lesão medular traumática: qual é o melhor método?

Andrea Ponte Rocha, Sergio Ricardo Menezes Mateus, Thomas Anthony Horan, Paulo Sérgio Siebra Beraldo

J Bras Pneumol.2009;35(3):256-260

Original Article

Comparative study of respiratory symptoms and lung function alterations in patients with chronic obstructive pulmonary disease related to the exposure to wood and tobacco smoke

Estudo comparativo de sintomas respiratórios e função pulmonar em pacientes com doença pulmonar obstrutiva crônica relacionada à exposição à fumaça de lenha e de tabaco

Maria Auxiliadora Carmo Moreira, Maria Rosedália de Moraes, Daniela Graner Schwartz Tannus Silva, Thayssa Faria Pinheiro, Huber Martins Vasconcelos Júnior, Lanucy Freita de Lima Maia, Daine Vargas do Couto

J Bras Pneumol.2008;34(9):661-666

Effects of expiratory positive airway pressure on the electromyographic activity of accessory inspiratory muscles in COPD patients

Efeitos da pressão positiva expiratória nas vias aéreas sobre a atividade eletromiográfica da musculatura acessória da inspiração em portadores de DPOC

Dannuey Machado Cardoso, Dulciane Nunes Paiva, Isabella Martins de Albuquerque, Renan Trevisan Jost, Andréia Vanessa da Paixão

J Bras Pneumol.2011;37(1):46-53

Reference equation for measurement of the maximal dynamic inspiratory muscle pressure index (S-Index) in healthy Brazilian adults

Luis Felipe da Fonseca Reis1, Cleber da Penha1, Pamela do Carmo Dosso da Silva1, Aline Oliveira Martins Soares de Mendonça1, Ana Carolina Sebastião da Silva1, Clara Pinto Diniz2, Flavia Mazzoli-Rocha2, Arthur de Sá Ferreira1, Agnaldo José Lopes1,3

J Bras Pneumol.2025;51(6):e20240312

Peak inspiratory flow in children and adolescents with asthma using dry powder inhalers: a cross-sectional study

Pico de fluxo inspiratório de crianças e adolescentes com asma que utilizam inaladores de pó: um estudo transversal

Caroline Palácio da Silva1a, Jean Silva Aretakis Cordeiro1, Murilo Carlos Amorim de Britto1, Patrícia Gomes de Matos Bezerra1, Lívia Barboza de Andrade1

J Bras Pneumol.2021;47(3):e20200473

Acceptability, preference, tolerance and clinical efficacy of dipropionate beclomethasone delivered by two inhalation devices in chronic asthma patients: Clenil pulvinal® versus Miflasona Aerolizer®

Avaliação da eficácia clínica, aceitabilidade e preferência de dois sistemas inalatórios de beclometasona no tratamento da asma : Pulvinal versus Aeroliser.

Jussara Fiterman, Waldo Mattos, Alberto Cukier, Márcia Pizzichinni, Rodnei Frare e Silva, Fabiane Kahan, José Roberto Jardim, Armando Brancatelli

J Bras Pneumol.2004;30(5):413-418

Impact of continuous positive airway pressure on the pulmonary changes promoted by immersion in water

Impacto da pressão positiva contínua nas vias aéreas sobre as alterações pulmonares promovidas pela imersão em água

Danize Aparecida Rizzetti1, Janayna Rodembuch Borba Quadros1, Bruna Esmerio Ribeiro1, Letícia Callegaro1, Aline Arebalo Veppo2, Giulia Alessandra Wiggers1, Franck Maciel Peçanha1

J Bras Pneumol.2017;43(6):409-415

Use of continuous positive airway pressure (CPAP) during physical activities on an ergometric treadmill performed by individuals with chronic obstructive pulmonary disease (COPD): comparison with the use of oxygen

Utilização da pressão positiva contínua nas vias aéreas (CPAP) durante atividade física em esteira ergométrica em portadores de doença pulmonar obstrutiva crônica (DPOC): comparação com o uso de oxigênio

Flávio Danilo Mungo Pissulin, Alcides Guimarães, Lúcio Benedicto Kroll, Michel Jorge Cecílio

J Bras Pneumol.2002;28(3):131-136

Effects of salbutamol delivered by dry-powder inhaler on methacholine-induced bronchoconstriction

Efeito do salbutamol liberado através de inalador de pó seco sobre o broncoespasmo induzido por metacolina

Adalberto Sperb Rubin, Liliana G Pelegrin,Christiano Perin, Maurício Roux Leite, Luiz Carlos Corrêa da Silva

J Bras Pneumol.2004;30(3):195-200

Background: Short-acting b2 agonists delivered by metered-dose inhaler (MDIs) are the drugs usually used for the reversal of methacholine-induced bronchoconstriction. The b2 agonists that are delivered by dry-powder inhaler (DPI) can be an efficacious option. Objective: To evaluate the effectiveness and speed of action of salbutamol delivered by DPI (Pulvinal; Butoventâ), in comparison to salbutamol delivered by MDI, in reversing methacholine-induced bronchoconstriction. Method: Sixty successive methacholine-induced bronchoconstriction patients who presented a decrease of at least 20% in forced expiratory volume (FEV1) were evaluated prospectively. Of these 60 patients, we randomized 30 (first group) to receive 200 mcg of salbutamol by MDI and 30 (second group) to receive 200 mcg of salbutamol by DPI (Pulvinal). Both drugs were administered with the objective of reversing bronchoconstriction during the final phase of a bronchoprovocation test. The FEV1 values obtained at 1 and 5 minutes after bronchodilator administration were evaluated. Results: The groups were comparable in gender distribution, age, weight, dose level provoking a 20% drop in FEV1 (first group: 1.3 mg; second group: 1.19 mg; p = 0.79) and post-methacholine FEV1 (first group: 2.03 l; second group: 1.99 l; p = 0.87), with no statistically significant differences between the two groups. In the first group (MDI), the mean increase in FEV1 was 16.2% (at 1 minute) and 22.2% (at 5 minutes), and in the second group (DPI) it was 17% (at 1 minute) and 23.6% (at 5 minutes). There was no statistically significant difference between the groups (p = 0.8). Conclusion: The b2-agonists delivered by DPI (Pulvinal) present the same bronchodilator efficacy and speed of action as do those delivered by the more traditional MDI method.

Keywords: Asthma. Bronchodilator agents/administration & dosage. Albuterol/administration & dosage. Methacholine chloride/administration & dosage. Respiratory therapy/methods. Administration, inhalation/methods. Prospective studies.

Impact of a mechanical ventilation weaning protocol on the extubation failure rate in difficult-to-wean patients

Impacto de um protocolo de desmame de ventilação mecânica na taxa de falha de extubação em pacientes de difícil desmame

Cassiano Teixeira, Juçara Gasparetto Maccari, Silvia Regina Rios Vieira, Roselaine Pinheiro Oliveira, Augusto Savi, André Sant'Ana Machado, Túlio Frederico Tonietto, Ricardo Viegas Cremonese, Ricardo Wickert, Kamile Borba Pinto, Fernanda Callefe, Fernanda Gehm, Luis Guilherme Borges, Eubrando Silvestre Oliveira

J Bras Pneumol.2012;38(3):364-371

Letters to the Editor

Incidence rate, clinical profile, and outcomes of COVID-19 in adults with noncystic fibrosis bronchiectasis

Cristiane Christ Camargo1, Fernanda de Miranda Schmitz2, Letícia Bauer Jacobsen1, Bruna Ziegler1,3, Paulo de Tarso Roth Dalcin1,2

J Bras Pneumol.2025;51(1):e20240258

Original Article

Yoga versus aerobic activity: effects on spirometry results and maximal inspiratory pressure

Ioga versus atividade aeróbia: efeitos sobre provas espirométricas e pressão inspiratória máxima

Dagoberto Vanoni de Godoy, Raquel Lonchi Bringhenti, Andréi Severa, Ricardo de Gasperi, Leonardo Vieira Poli

J Bras Pneumol.2006;32(2):130-135

Maximal dynamic inspiratory pressure: S-Index prediction values and diagnosis accuracy

Vitor Costa Souza1, Maria Fernanda Lima Souza Saldanha1, Eloara Vieira Machado Ferreira1, Luiz Eduardo Nery1, Priscila Cristina de Abreu Sperandio1

J Bras Pneumol.2025;51(4):e20240409

Reference values for sniff nasal inspiratory pressure in healthy subjects in Brazil: a multicenter study

Valores de referência da pressão inspiratória nasal em indivíduos saudáveis no Brasil: estudo multicêntrico

Palomma Russelly Saldanha de Araújo, Vanessa Regiane Resqueti, Jasiel Nascimento Jr, Larissa de Andrade Carvalho, Ana Gabriela Leal Cavalcanti, Viviane Cerezer Silva, Ester Silva, Marlene Aparecida Moreno, Arméle de Fátima Dornelas de Andrade, Guilherme Augusto de Freitas Fregonezi

J Bras Pneumol.2012;38(6):700-707

Comparing peak and sustained values of maximal respiratory pressures in healthy subjects and chronic pulmonary disease patients

Comparação entre os valores de pico e sustentados das pressões respiratórias máximas em indivíduos saudáveis e pacientes portadores de pneumopatia crônica

J Bras Pneumol.2003;29(4):208-212

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