Original Article

Tuberculosis-related mortality in the state of Espírito Santo, Brazil, 1985-2004

Mortalidade específica por tuberculose no estado do Espírito Santo, no período de 1985 a 2004

Cláudia Maria Marques Moreira, Eliana Zandonade, Reynaldo Dietze, Ethel Leonor Noia Maciel

J Bras Pneumol.2008;34(8):601-606

Letters to the Editor

Potential years of life lost by COVID-19 in the state of Espírito Santo and proportional mortality by age.

Anos potenciais de vida perdidos devido à COVID-19 no estado do Espírito Santo e mortalidade proporcional por idade.

Keila Cristina Mascarello1, Anne Caroline Barbosa Cerqueira Vieira1, Paula de Souza Silva Freitas2, Helaine Jacinta Salvador Mocelin2, Ethel Leonor Noia Maciel2

J Bras Pneumol.2022;48(1):e20210489

Original Article

Completeness of tuberculosis control program records in the case registry database of the state of Espírito Santo, Brazil: analysis of the 2001-2005 period

Completude dos dados do Programa de Controle da Tuberculose no Sistema de Informação de Agravos de Notificação no Estado do Espírito Santo, Brasil: uma análise do período de 2001 a 2005

Cláudia Maria Marques Moreira, Ethel Leonor Noia Maciel

J Bras Pneumol.2008;34(4):225-229

Epidemiological profile of adult patients with tuberculosis and AIDS in the state of Espírito Santo, Brazil: Cross-referencing tuberculosis and AIDS databases

Perfil epidemiológico de pacientes adultos com tuberculose e AIDS no estado do Espírito Santo, Brasil: Relacionamento dos bancos de dados de tuberculose e AIDS

Thiago Nascimento do Prado, Antonio Luiz Caus, Murilo Marques, Ethel Leonor Maciel, Jonathan E. Golub, Angélica Espinosa Miranda

J Bras Pneumol.2011;37(1):93-99

Mortality due to idiopathic pulmonary fibrosis in the State of Rio Grande do Sul (Brazil)

Mortalidade por fibrose pulmonar idiopática no Rio Grande do Sul

Fabrício Picolli Fortuna, Christiano Perin, Letícia Cunha, Adalberto Sperb Rubin

J Bras Pneumol.2003;29(3):121-124

Brief Communication

Temporal trends in tuberculosis-related morbidity and mortality in the state of Santa Catarina, Brazil, between 2002 and 2009

Tendência temporal da morbidade e mortalidade por tuberculose no estado de Santa Catarina, Brasil, no período entre 2002 e 2009

Jefferson Traebert, Glênio César Nunes Ferrer, Nazaré Otília Nazário, Ione Jayce Ceola Schneider, Rosemeri Maurici da Silva

J Bras Pneumol.2012;38(6):757-760

Original Article

Spatial analysis of deaths from pulmonary tuberculosis in the city of São Luís, Brazil

Análise espacial dos óbitos por tuberculose pulmonar em São Luís, Maranhão

Marcelino Santos-Neto, Mellina Yamamura, Maria Concebida da Cunha Garcia, Marcela Paschoal Popolin, Tatiane Ramos dos Santos Silveira, Ricardo Alexandre Arcêncio

J Bras Pneumol.2014;40(5):543-551

Asthma morbidity and mortality in the State of Parana and in city of Curitiba from 1984 to 1995

Morbimortalidade por asma no Estado do Paraná e município de Curitiba no período entre 1984 e 1995

Sônia Zulato, Denise Carvalho, Anne-Claire Ribeiro, Nelson Augusto Rosário Filho

J Bras Pneumol.1999;25(1):12-16

The burden of disease due to tuberculosis in the state of Santa Catarina, Brazil

A carga de doença por tuberculose no estado de Santa Catarina

J Bras Pneumol.2014;40(1):61-68

Evaluation of surveillance of contacts of new tuberculosis cases in the state of Mato Grosso - Brazil

Avaliação da vigilância de contatos de casos novos de tuberculose no Estado de Mato Grosso - Brasil

Shaiana Vilella Hartwig, Eliane Ignotti, Beatriz Fátima Alves de Oliveira, Hellen Caroline de Oliveira Pereira, João Henrique Scatena

J Bras Pneumol.2008;34(5):298-303

Prevalence of allergic bronchopulmonary aspergillosis in patients with cystic fibrosis in the state of Bahia, Brazil

Prevalência de aspergilose broncopulmonar alérgica em pacientes com fibrose cística na Bahia, Brasil

Ana Cláudia Costa Carneiro, Antônio Carlos Moreira Lemos, Sérgio Marcos Arruda, Maria Angélica Pinheiro Santos Santana

J Bras Pneumol.2008;34(11):900-906

Mortality due to pneumoconioses in macro regions of Brazil in the 1979-1998 period

Mortalidade por pneumoconioses nas macrorregiões do Brasil no período de 1979-1998

Hermano Albuquerque de Castro, Genésio Vicentin, Kellen Cristina Xavier Pereira

J Bras Pneumol.2003;29(2):82-88

Tuberculosis in a medium-sized city in the Southeast of Brazil: morbidity and mortality rates (1985 - 2003)

Tuberculose em município de porte médio do sudeste do Brasil: indicadores de morbidade e mortalidade, de 1985 a 2003

Silvia H. F. Vendramini, Cláudia Eli Gazetta, Francisco Chiaravalotti Netto, Maria R. Cury, Edna B. Meirelles, Fátima G. Kuyumjian, Tereza C. S. Villa

J Bras Pneumol.2005;31(3):237-243

Background: Tuberculosis is a disease linked to poverty, unequal distribution of wealth, and urbanization, as well as the epidemics of acquired immunodeficiency syndrome epidemic and multidrug resistance. Objective: To analyze indicators of tuberculosis morbidity and mortality in the city of São José do Rio Preto, Brazil from 1985 to 2003, compared with those in the state of São Paulo and in Brazil at large, and to determine the relationship between the risk of occurrence and socioeconomic level. Method: The following official information systems were utilized: the Sistema de Informação de Mortalidade (SIM, Mortality database), the Notificação de Tuberculose (Epi-Tb, Tuberculosis Notification database), the Sistema de Informação de Agravos de Notificação (SINAN, Case-registry database), the Departamento de Informação e Informática do Sistema Único de Saúde (DATASUS, Information Department of the Brazilian Health Ministry) and the Instituto Brasileiro de Geografia e Estatística (IBGE, Brazilian Institute of Geography and Statistics database). New cases reported in 2003 in the urban area were georeferenced and analyzed. A map of the sectors, each classified as representing one of three socioeconomic classes, was drawn up, showing the respective tuberculosis incidence coefficients. Results: Comparing Brazil as a whole to the state of São Paulo, total incidence coefficients and mortality rates were similar, as were gender-related values. In the city of São José do Rio Preto the rates were consistently lower. The proportion of cases presenting tuberculosis/human immunodeficiency virus coinfection varied from 29% to 37%. In 2002, 59% and 65% of tuberculosis-only and coinfected tuberculosis patients, respectively, were under supervised treatment, with a cure rate of 81% and a treatment-abandonment rate of 1%. The risk of developing active tuberculosis was three times higher in the area presenting the lowest socioeconomic levels. Conclusion: Identification of the areas with different levels of risks for tuberculosis enables the Municipal Health Department to deal with the peculiarities of each region and to prioritize those presenting higher incidences of the disease.

Keywords: Tuberculosis. Epidemiology. Socioeconomic class. Supervised Treatment. Infection. HIV.

Drug resistance profile of Mycobacterium tuberculosis in the state of Mato Grosso do Sul, Brazil, 2000-2006

Perfil de resistência de Mycobacterium tuberculosis no estado de Mato Grosso do Sul, 2000-2006

Marli Marques, Eunice Atsuko Totumi Cunha, Antonio Ruffino-Netto, Sonia Maria de Oliveira Andrade

J Bras Pneumol.2010;36(2):224-231

Objective: To determine the drug resistance profile of Mycobacterium tuberculosis in the state of Mato Grosso do Sul, Brazil, between 2000 and 2006. Methods: Descriptive study of reported tuberculosis cases in the Brazilian Case Registry Database. We included only those cases in which M. tuberculosis culture was positive and sensitivity to drugs (rifampicin, isoniazid, streptomycin and ethambutol) was tested. Löwenstein-Jensen and Ogawa-Kudoh solid media were used for cultures, as was an automated liquid medium system. Sensitivity tests were based on the proportion method. Results: Among the 783 cases evaluated, males predominated (69.7%), as did patients in the 20-49 year age bracket (70%), a diagnosis of pulmonary tuberculosis (94.4%) and positive HIV serology (8.6%); 645 (82.4%) were new cases, and 138 (17.6%) had previously been treated. Resistance to at least one drug was found in 143 cases (18.3%). The primary resistance (PR) rate was, respectively, 8.1%, 1.6%, 2.8% and 12.4%, for monoresistance, multidrug resistance (MDR), other patterns of resistance and resistance to at least one drug, whereas the acquired resistance (AR) rate was 14.5%, 20.3%, 10.9% and 45.7%, respectively, and the combined resistance (CR) rate was 9.2%, 4.9%, 4.2% and 18.3%, respectively. In PR, streptomycin was the most common drug, whereas isoniazid was the most common in AR and CR (7.2% and 3.7%, respectively). Conclusions: These high levels of resistance undermine the efforts for tuberculosis control in Mato Grosso do Sul. Acquired MDR was 12.7 times more common than was primary MDR, demonstrating that the previous use of drug therapy is an indicator of resistance. These levels reflect the poor quality of the health care provided to these patients, showing the importance of using the directly observed treatment, short course strategy, as well as the need to perform cultures and sensitivity tests for the early diagnosis of drug resistance.

Keywords: Tuberculosis; Drug resistance, multiple; Mycobacterium tuberculosis.

Epidemiological aspects of pleural tuberculosis in the state of São Paulo, Brazil (1998-2005)

Aspectos epidemiológicos da tuberculose pleural no estado de São Paulo (1998-2005)

Márcia Seiscento, Francisco Suso Vargas, Maria Josefa Penon Rujula, Sidney Bombarda, David Everson Uip, Vera Maria Nedes Galesi

J Bras Pneumol.2009;35(6):548-554

Factors associated with delayed diagnosis of pulmonary tuberculosis in the state of Rio de Janeiro, Brazil

Fatores associados ao atraso no diagnóstico da tuberculose pulmonar no estado do Rio de Janeiro

Audry Cristina de Fátima Teixeira Machado, Ricardo Ewbank Steffen, Olivia Oxlade, Dick Menzies, Afrânio Kritski, Anete Trajman

J Bras Pneumol.2011;37(4):512-520

Characteristics of tuberculosis in the state of Minas Gerais, Brazil: 2002-2009

Características da tuberculose no estado de Minas Gerais entre 2002 e 2009

Cláudio José Augusto, Wânia da Silva Carvalho, Alan Douglas Gonçalves, Maria das Graças Braga Ceccato, Silvana Spindola de Miranda

J Bras Pneumol.2013;39(3):357-364

Objective: To analyze the profile of tuberculosis cases reported between 2002 and 2009 in the state of Minas Gerais, Brazil, according to sociodemographic, clinical, and laboratory characteristics, as well as to comorbidities and mortality. Methods: This was a descriptive, epidemiological study based on data obtained from the Brazilian Case Registry Database and the Brazilian Mortality Database for the 2002-2009 period. Results: There were 47,285 reported cases of tuberculosis, corresponding to a mean incidence of 22.3/100,000 population. The individuals diagnosed with tuberculosis were predominantly in the 20- to 49-year age bracket and male (62.4% and 67.0%, respectively). Individuals with a low level of education accounted for 18.5% of the cases. New cases, cases of recurrence, and cases of retreatment accounted for 83.7%, 5.7%, 5.7%, respectively. The rates of cure and treatment noncompliance were 66.2% and 11.2%, respectively; multidrug-resistant tuberculosis was identified in 0.2% of the cases; and the mortality rate was 12.9%. The directly observed treatment, short-course (DOTS) strategy was applied in 21.8% of the cases. Sputum smear microscopy and culture were performed in only 73.9% and 12.9% of the cases, respectively. Chest X-rays were performed in 90.5% of the cases. Pulmonary tuberculosis was the predominant form (in 83.9%). Comorbidity with alcoholism, HIV infection, and diabetes mellitus were identified in 17.2%, 8.3%, and 3.8%, respectively. Conclusions: During the study period, the numbers of new cases, cases of treatment noncompliance, and deaths were high, comorbidities were common, and there was a failure to perform adequately basic tests for the diagnosis of tuberculosis. Multidisciplinary approaches, expanded use of the DOTS strategy, better knowledge of the distribution of tuberculosis, and improvements in the databases are needed in order to achieve better control of the disease in the state of Minas Gerais.

Keywords: Tuberculosis/epidemiology; Tuberculosis/mortality; Information systems.

Pleural tuberculosis in the state of Roraima, Brazil, between 2005 and 2013: quality of diagnosis

Tuberculose pleural no estado de Roraima no período de 2005-2013: qualidade diagnóstica

Tao Machado1, Allex Jardim da Fonseca2, Sandra Maria Franco Buenafuente2

J Bras Pneumol.2016;42(2):106-113

Brief Communication

Tuberculosis and gender in a priority city in the state of Rio de Janeiro, Brazil

Tuberculose e gênero em um município prioritário no estado do Rio de Janeiro

Márcia Teresa Carreira Teixeira Belo, Ronir Ragio Luiz, Christy Hanson, Lia Selig, Eleny Guimarães Teixeira, Thiago Chalfoun, Anete Trajman

J Bras Pneumol.2010;36(5):621-625

Original Article

Noncompliance with treatment for pulmonary tuberculosis in Cuiabá, in the State of Mato Grosso - Brazil

Abandono do tratamento da tuberculose pulmonar em Cuiabá - MT - Brasil

Silvana Margarida Benevides Ferreira, Ageo Mário Cândido da Silva, Clóvis Botelho

J Bras Pneumol.2005;31(5):427-435

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